A novel radiation-induced p53 mutation is not implicated in radiation resistance via a dominant-negative effect.

PLoS One · 2014 · PMC3928108 · PMID 24558369

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slightly significantno p-value reported

At lower radiation doses, WT p53 conferred a slightly significant survival advantage in H1299 cells; however, after a dose of 6 Gy, there was no difference in the survival of H1299 cells, regardless of p53 mutation status.

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