Dietary quercetin supplementation in mice increases skeletal muscle PGC1α expression, improves mitochondrial function and attenuates insulin resistance in a time-specific manner.

Additionally, HF+50Q but not HF+600Q experienced a decrease in plasma blood glucose levels at 8 wks, although this decrease did not reach statistical significance compared to HF but did when compared to HF+600Q ( Fig. 3F ).

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