A study of gene expression markers for predictive significance for bevacizumab benefit in patients with metastatic colon cancer: a translational research study of the Hellenic Cooperative Oncology Group (HeCOG).

Finally, the profile of all-low (ALDH6A1 + TFF2) tumor gene expression showed a marginally significant association with superior survival in the chemotherapy-only Control set, but not in the Bevacizumab qPCR set (Table 3 ).

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KLF12 was the only gene that could not be validated in the test set with qPCR; high transcript levels of this gene were, however, showed a trend for better outcome in the validation set.

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