Nanostructured lipid carriers as a novel oral delivery system for triptolide: induced changes in pharmacokinetics profile associated with reduced toxicity in male rats.

Int J Nanomedicine · 2014 · PMC3934590 · PMID 24591827

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did not reach statistical significanceno p-value reported

As shown in Figure 10 , at the high dose level, in contrast with free TP, TP-NLCs showed significantly decreased oxidative stress as indicated by the increase in SOD activity and reduction of MDA formation ( P <0.05), while the differences did not reach statistical significance in TP-SLNs.

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