Regulation of DNA methyltransferase 1 transcription in BRCA1-mutated breast cancer: a novel crosstalk between E2F1 motif hypermethylation and loss of histone H3 lysine 9 acetylation.

Moreover, patients with premenopausal (Figure 6 B, P = 0.155), estrogen receptor-negative (Figure 6 F, P = 0.170) and p53-negative (Figure 6 I, P = 0.089) breast cancer showed a trend for poor overall survival, although this was not statistically significant.

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