showed a trendP = 0.147
The analysis showed a trend in favor of the LET + ZOL treatment (OR = 1.72; 95% CI, 0.827 to 3.586; P = 0.147).
The analysis showed a trend in favor of the LET + ZOL treatment (OR = 1.72; 95% CI, 0.827 to 3.586; P = 0.147).
Discussion In this prematurely terminated, randomized phase II study in postmenopausal women with hormone receptor–positive primary breast cancer, a positive trend in the clinical tumor response was observed with the addition of zoledronic acid to neoadjuvant treatment with letrozole.