The detailed analysis showed a clear trend towards decreased number of TLR4 positive insulin producing cells in diabetic mice that coincided with a statistically 3-fold increase of TLR4 positive macrophages locally in the islets.
← all excerpts
Macrophage contact dependent and independent TLR4 mechanisms induce β-cell dysfunction and apoptosis in a mouse model of type 2 diabetes.
1
—
—