Neuropsychological and behavioral profiles in attention-deficit hyperactivity disorder children of parents with a history of mood disorders: a pilot study.

Although the high-risk group showed a trend of more use of atypical antipsychotics compared to the low-risk group, atypical antipsychotic appears to have no detrimental effect on cognitive performance in children. 61 We extended the findings of previously studied high-risk offspring using a more narrowly defined high-risk group characterized by ADHD and a family history of a mood disorder, using both healthy controls and ADHD children without a family history of a mood disorder as comparison groups, and by adjusting for the influence of mood ratings and familial functioning when assessing cognitive and behavioral group differences.

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