highly significantP < 0.0001
The greatest mean IOP change was found in Group A, with a highly significant mean IOP change of -7.4 ± 3.8 mmHg (-29.7%) at week 1, -8.0 ± 3.3 mmHg (-32.0%) at month 1, and -8.0 ± 3.7 mmHg (-32.0%) at month 3 (all P < 0.0001 compared with baseline).