Cluster 4 showed a trend toward decreased time interval from brain metastasis to death with a median time of 4.1 (range 1.9–28.0) months versus 15.1 (range 2.6–73.3) months for the rest of the melanoma cohort ( P =0.117, Table 3B ).
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Melanoma brain metastasis globally reconfigures chemokine and cytokine profiles in patient cerebrospinal fluid.
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