Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene.

Results and Discussion In the present replication effort, a nominally significant signal ( P <0.05) was detected for six of the 19 investigated SNPs: rs35349669 at INPP5D ( P =0.023); rs190982 at MEF2C ( P =0.0062); rs1476679 at ZCWPW1 ( P =0.00065); rs17125944 at FERMT2 ( P =0.018); rs8035452 at SPPL2A ( P =0.031); and rs74615166 at TRIP4 ( P =0.0032) ( Table 1 ).

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