Genome-wide DNA methylation analysis predicts an epigenetic switch for GATA factor expression in endometriosis.

PLoS Genet · 2014 · PMC3945170 · PMID 24603652

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highly significantno p-value reported

One remarkable finding from this analysis was that it correctly identified the HOXA cluster, NR5A1 , and PGR —genes that are aberrantly methylated and differentially expressed in endometriosis—as highly significant.

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did not reach statistical significanceno p-value reported

Silencing GATA6 decreased basal CYP19A1 by 87%, although this did not reach statistical significance.

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