In both tests the PbA-infected mice treated with artesunate/mefloquine alone showed impaired performance compared with uninfected controls, however the difference between the groups did not reach statistical significance (p = 0.063 for constant rotarod test, and p = 0.12 for accelerating rotarod test).
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PPARγ agonists improve survival and neurocognitive outcomes in experimental cerebral malaria and induce neuroprotective pathways in human malaria.
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0.0630
0.0630