Elevated high-density lipoprotein cholesterol and age-related macular degeneration: the Alienor study.

PLoS One · 2014 · PMC3946623 · PMID 24608419

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)

After further adjustment for educational level, smoking, BMI, lipid-lowering medication use, cardiovascular disease and diabetes, higher HDL remained significantly associated with an increased risk of early (OR = 1.71, P = 0.008) or any AMD (OR = 1.83, P = 0.002) and tended to be associated with increased risk of late AMD, but did not reach statistical significance (OR = 2.58, P = 0.06) especially after Bonferroni correction.

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highly significantno p-value reported

However, we adjusted for this by using Bonferroni correction with many associations remaining highly significant.

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