Our study would not determine the potential SNP or indel variation in the SVA; such variation may be significant for both clinical association with disease and transcriptional properties of the SVA.
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An evaluation of a SVA retrotransposon in the FUS promoter as a transcriptional regulator and its association to ALS.
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The sentences
Preliminary analysis addressed the association of these SVA variants within a small sporadic ALS cohort but did not reach statistical significance, although we did not include other parameters such as SNPs within the SVA or an environmental factor in this analysis.