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Inhibition of ceramide de novo synthesis with myriocin affects lipid metabolism in the liver of rats with streptozotocin-induced type 1 diabetes.

Biomed Res Int · 2014 · PMC3950399 · PMID 24701589

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However, we observed only a trend which did not reach statistical significance in Akt/PKB expression in myriocin treated group, but surprisingly we found that administration of myriocin resulted in significant increase of pAkt/PKB expression.

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