failed to reach significanceP = 0.0623
Although the combination of rosiglitazone and T0070907 resulted in a downward trend of PPAR- γ expression levels when compared to vehicle control, this failed to reach significance ( P = 0.0623).
Although the combination of rosiglitazone and T0070907 resulted in a downward trend of PPAR- γ expression levels when compared to vehicle control, this failed to reach significance ( P = 0.0623).
Although these results did not reach statistical significance, they may be explained by the incomplete receptor knockdown as well as the presence of the autoregulatory PPAR- γ feedback mechanism.