Impact of IL28B genetic variation on HCV-induced liver fibrosis, inflammation, and steatosis: a meta-analysis.

PLoS One · 2014 · PMC3956722 · PMID 24637774

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0.0760

closest p · 1.5× alpha

0.0760

boldest claim

The sentences

did not reach statistical significanceP = 0.076so close (0.05 < p ≤ 0.1)

For rs8099917, there was no or low heterogeneity (I 2 = 31%, P = 0.111), and IL28B rs8099917 genotype TT tended to be associated with a higher possibility of severe fibrosis; however, the difference did not reach statistical significance (OR, 1.126; 95%CI, 0.988–1.284; P = 0.076) ( Fig. 2-b ).

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