Clinical and prognostic significance of HIF-1α, PTEN, CD44v6, and survivin for gastric cancer: a meta-analysis.

PLoS One · 2014 · PMC3960154 · PMID 24647137

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Subgroup analysis showed a trend that reduced PTEN levels were associated with the following factors: depth of invasion (12 studies, 1599 patients; OR = 2.604, 95% CI = 1.554–4.366, P<0.001); lymph node metastasis (18 studies, 2258 patients; OR = 2.484, 95% CI = 1.836–3.360, P<0.001); distant metastasis (9 studies, 1393 patients;

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