Light stimulates the mouse adrenal through a retinohypothalamic pathway independent of an effect on the clock in the suprachiasmatic nucleus.

Ishida et al., [9] reported a light-evoked increase in corticosterone secretion at CT16 using 400 lux light stimulation but the light-evoked change in plasma corticosterone at CT4 did not reach statistical significance, perhaps due to the small number of animals stimulated with light (n = 4).

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