Off-pump coronary artery bypass grafting (OPCABG): the beginning of the end?

In contrast, the primary composite endpoint was lower for OPCABG in both the Coronary and GOPCABE trials, although this did not reach statistical significance.

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Likewise, Kuss and colleagues analysed 38 propensity matched studies of 123,137 patients and again reported highly significant reductions in the risk of mortality, stroke, renal failure, prolonged ventilation and other aspects of morbidity with off pump surgery. 12 One possible explanation for the apparent differences between the randomised trials and the registries is the suggestion that the major benefits of OPCABG surgery appear when the predicted mortality for CABG exceeds 5%.

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