Although we had a limited number of samples, a clear trend could be observed towards an increased expression of EFEMP1 in glioblastoma samples at the time of progression (Fig. 6C ), suggesting that EFEMP1 could be used as a marker for tumor progression after TMZ treatment.
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EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma.
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