The role of M1 and M2 macrophages in prostate cancer in relation to extracapsular tumor extension and biochemical recurrence after radical prostatectomy.

Moreover, when we stratified our patients for M1 and M2 macrophage phenotypes, we did not find any statistical difference among BCR free survival curves (log rank P = ns ), although we observed that patients with prevalence of M2 macrophages showed a trend toward worst BCR free survival rates at 36 and 60 months compared to patients with M1 prevalence (78.2 versus 94.1 and 71.0 versus 77.4, resp.) (see Figure 3 ).

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