Impact of the common genetic associations of age-related macular degeneration upon systemic complement component C3d levels.

PLoS One · 2014 · PMC3968152 · PMID 24675670

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showed a trendno p-value reported

Variants in CFB rs4151667, TIMP3 rs9621532 and APOE4 rs429358 showed a trend for a protective effect on AMD without reaching statistical significance, which may be due to low minor allele frequencies or smaller effects of those SNPs.

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