Lesions of the lateral habenula increase voluntary ethanol consumption and operant self-administration, block yohimbine-induced reinstatement of ethanol seeking, and attenuate ethanol-induced conditioned taste aversion.

Though lesioned rats consumed more saccharin than sham rats in every time period except the first hour of access, this difference did not reach statistical significance (no main effect of lesion, F(1, 12) = 3.2, NS; and no significant interaction of lesion x time, F(3, 36) = 1.2, NS).

also in 111,027 other papers