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Microglia receptors and their implications in the response to amyloid β for Alzheimer's disease pathogenesis.

J Neuroinflammation · 2014 · PMC3975152 · PMID 24625061

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In the last decade, several candidate drugs have failed to reach statistical significance in their primary outcomes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.