Furthermore, cytokine analysis showed a trend toward increased serum Th17/Th1 ratios when P. gingivalis infection was present in mice receiving either CFA/CII or IFA/CII immunizations.
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Porphyromonas gingivalis oral infection exacerbates the development and severity of collagen-induced arthritis.
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gingivalis oral infection was present in mice developing arthritis in the CFA/CII group compared with CFA/CII alone, and a nonsignificant trend in IL-17F/IFNγ ratios (Figure 4 B).