Effect of screening sigmoidoscopy and screening colonoscopy on colorectal cancer incidence and mortality: systematic review and meta-analysis of randomised controlled trials and observational studies.

BMJ · 2014 · PMC3980789 · PMID 24922745

Europe PMC DOI

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failed to reach statistical significanceno p-value reported

With relative risks between 0.69 and 0.78 in intention to screen analysis, effect estimates for total colorectal cancer mortality were close in all the trials (even though the estimate failed to reach statistical significance in the Italian trial), suggesting a 22-31% reduction in overall colorectal cancer mortality.

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