Immune dysregulation as a cause of autoinflammation in fragile X premutation carriers: link between FMRI CGG repeat number and decreased cytokine responses.

PLoS One · 2014 · PMC3981824 · PMID 24718368

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did not reach statistical significanceno p-value reported

105.1 pg/mL (27.1–408.1 pg/mL); p = 0.08) showed trends towards decreased production in premutation carriers, and approached but did not reach statistical significance.

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failed to reach significanceno p-value reported

After stimulation with LPS, cytokines such as IL-1β (p = 0.06), IL-12(p40) (p = 0.08) showed similar trends of decreasing levels that were associated with CGG repeat length, but failed to reach significance ( Table 1 ) .

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