Induction of lung cancer cell apoptosis through a p53 pathway by [6]-shogaol and its cysteine-conjugated metabolite M2.

J Agric Food Chem · 2014 · PMC3983336 · PMID 24446736

Europe PMC DOI

hedged sentences

0.0669

closest p · 1.3× alpha

0.0678

boldest claim

The sentences

close to being significantp = 0.0669so close (0.05 < p ≤ 0.1)

In the case of the animals treated with M2 30 mg/kg, we also observed the same trend (28.6 TUNEL+ cells/field) that was very close to being significant ( p = 0.0669).

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very close to significancep = 0.0678so close (0.05 < p ≤ 0.1)

We also detected a marked reduction of cell proliferation in the 6S 10 mg/kg group (4.7 BrdU+ cells/field) that was very close to significance ( p = 0.0678 by unpaired t test compared to control).

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a clear trendno p-value reported

However, there was still a clear trend and it is probable that the number of animals used was not sufficient and that an increased number would allow for the detection of a significant induction of apoptosis even by M2 (Figure 6 C).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.