Circulating irisin levels are not affected by coffee intake: a randomized controlled trial.

PLoS One · 2014 · PMC3984159 · PMID 24728416

Europe PMC DOI

hedged sentences

0.7500

closest p · 15.0× alpha

0.7500

boldest claim

The sentences

did not reach statistical significancep = 0.75not close (p > 0.1)

Though there was a trend towards increased levels of irisin over time in the caffeinated coffee group (+1.8%) when compared to the placebo group (−4%) this did not reach statistical significance (p = 0.75 for the trend).

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failed to reach significanceno p-value reported

In further support of this theory, though these associations failed to reach significance likely due to our small sample size, irisin tended to be positively associated with markers of inflammation and HOMA-IR and inversely related to the insulin-sensitizing hormone adiponectin.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.