Systemic neutralization of IL-17A significantly reduces breast cancer associated metastasis in arthritic mice by reducing CXCL12/SDF-1 expression in the metastatic niches.

BMC Cancer · 2014 · PMC3986611 · PMID 24674692

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did not reach statistical significanceno p-value reported

Data demonstrates that adding anti-CXCR4 neutralizing antibody to the 4 T1 and PyV MT tumor cells in the upper chamber had some effect on % migration, but in most instances the difference did not reach statistical significance (Figures 5 C-E bar# 1 versus bar# 5, and Figures 5 C-F bar# 3 versus bar# 6).

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