The FGFR1 + or BRF2 + patients survived longer than those with no or low copy number gain, although this difference did not reach statistical significance ( FGFR1 , P = 0.324; BRF2 , P = 0.179) ( figures 2E and 2F ).
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Increased SOX2 gene copy number is associated with FGFR1 and PIK3CA gene gain in non-small cell lung cancer and predicts improved survival in early stage disease.
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