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Whole blood interferon-γ release assay is insufficient for the diagnosis of sputum smear negative pulmonary tuberculosis.

Yonsei Med J · 2014 · PMC3990062 · PMID 24719140

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Our study demonstrated that while sputum showed a negative tendency, it did not reach statistical significance between the PTB and non-TB group and that weight loss was the only positive predictor of active PTB in sputum smear negative PTB suspects.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.