a strong trendP = 0.05
Expression increases in miR-186 from post- to 60 min post-exercise (fold change = 1.58, P <0.001) paralleled a significant upregulation of SIRT6 mRNA (fold change = 1.66, P <0.05), a significant downregulation of TERF2IP mRNA (fold change = 0.54, P <0.01) and a strong trend towards significance for RAD50 (fold change = 0.76, P = 0.05).