The pemetrexed-containing treatments in the non-small cell lung cancer is -/low thymidylate synthase expression better than +/high thymidylate synthase expression: a meta-analysis.

Although the objective response rate difference did not reach statistical significance between patients treated with platinum-free and platinum containing subgroup, −/low TS expression patients treated with pemetrexed plus cisplatin or carboplatin might be more likely to achieve complete or partial response.

also in 111,027 other papers