Thymidylate synthase polymorphisms in genomic DNA as clinical outcome predictors in a European population of advanced non-small cell lung cancer patients receiving pemetrexed.

J Transl Med · 2014 · PMC3996904 · PMID 24726028

Europe PMC DOI

hedged sentence

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

a clear trendp = 0.055so close (0.05 < p ≤ 0.1)

With regards to the TSER polymorphisms, the presence of a 3R/3R polymorphism seemed to predict a higher ORR with a clear trend toward statistical significance (p = 0.055).

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