In tissue level, we analyzed the effect on let-7a SNP genotypes on its mature let-7a expression in gastric cancer tissue, and found rs629367 AA, CA, CC genotype also showed a tendency of gradually increasing, although this difference did not reach statistical significance ( Table 4 ).
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A new polymorphism biomarker rs629367 associated with increased risk and poor survival of gastric cancer in chinese by up-regulated miRNA-let-7a expression.
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