In a multivariate Cox proportional-hazards regression analysis, high fascin expression only reached borderline significance as an independent predictor of poor survival, with a hazard ratio of 0.663 (95% confidence interval: 0.44−1; P = .05) ( Supplementary Table 1 ).
← all excerpts
Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes.
2
0.0500
0.0500
The sentences
Fascin expression contributes to progression of human PDAC, but is only of borderline significance as a prognostic indicator, indicating that other factors contribute to recurrence and spread.