Interleukin-17 retinotoxicity is prevented by gene transfer of a soluble interleukin-17 receptor acting as a cytokine blocker: implications for age-related macular degeneration.

PLoS One · 2014 · PMC4004582 · PMID 24780906

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near-significantno p-value reported

Injection of AAV2.sIL17R resulted in sIL17R protein expression, no change in retinal Il17a transcripts, and a near-significant reduction in Il6 ( Figure S1C–E ), supporting sIL17R expression in AAV2.sIL17R- but not in AAV2.EV-treated eyes.

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