Loss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosis.

PLoS One · 2014 · PMC4008566 · PMID 24788138

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did not reach statistical significanceno p-value reported

In our in vivo model, expression of Kit D814V and simultaneous deletion of Tet2 in mature mast cells in the skin using the Mcpt5-Cre driver appeared to cause a more aggressive disease phenotype, but the difference between genotypes did not reach statistical significance.

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