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The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs.

PLoS One · 2014 · PMC4010412 · PMID 24796678

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The sixth gene, CD177 , had the same direction of change in SLE samples but the change did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.