Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts.

PLoS One · 2014 · PMC4010529 · PMID 24797518

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Phosphorylation of p53 S20 was not readily detectable, but p21 Cip1 levels showed a trend towards being elevated in SV40 immortalized Poldip2−/− MEFs, similar to untransformed Poldip2−/− MEFs ( Figure 8D and 5D ).

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