Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: results of the ALFA-0701 trial.

Moreover, the OS benefit associated with GO treatment appeared more pronounced in FLT3 –ITD positive than in negative patients, in the whole cohort as well as in CN-AML (Figure 4 ), although the Gail and Simon test did not reach statistical significance (Figure 3 ).

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