Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma.

Hum Mol Genet · 2014 · PMC4014188 · PMID 24403052

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantP = 5.5 × 10 −17actually significant

Combined with the Icelandic data, the overall association is highly significant ( P = 5.5 × 10 −17 , OR = 1.29 for rs214782; Table 1 , Supplementary Material, Table S4 ).

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nominally significantno p-value reported

Conditional analysis of the Icelandic data showed that rs59586681 ( Distal ) retains a nominally significant signal once the effect of rs214782 ( Top ) is taken into account ( P adj = 1.8 × 10 −4 , OR adj = 0.90).

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