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Pioglitazone and metformin are equally effective in reduction of chemerin in patients with type 2 diabetes.

J Diabetes Investig · 2014 · PMC4020338 · PMID 24843782

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Systolic blood pressure of the pioglitazone group patients was slightly higher; however, this difference did not reach statistical significance (mean difference 5.12 mmHg, 95% confidence interval −10.35 to 0.10).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.