7) Interestingly, at the doses tested, R -ketamine produced a state of relaxation and elation, which was correctly identified as a drug effect by all subjects, even though R -ketamine produced an only marginally significant change in mood scores. 7) Taken together, these data suggest that the R -stereoisomer of ketamine would be an alternative antidepressant for ketamine as R -ketamine may be free of psychotomimetic side effects.
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The R-Stereoisomer of Ketamine as an Alternative for Ketamine for Treatment-resistant Major Depression.
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