Using colony formation assay, although DKK1-transfectants displayed a tendency of increased colonies (Figure 2 G), and shDKK1-transfectants showed a reduced tendency (Figure 2 H), however, the difference did not reach statistical significance, compared with their control cells respectively.
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DKK1 promotes hepatocellular carcinoma cell migration and invasion through β-catenin/MMP7 signaling pathway.
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