Loss of synaptic connectivity, particularly in second order neurons is a key feature of diabetic retinal neuropathy in the Ins2Akita mouse.

PLoS One · 2014 · PMC4029784 · PMID 24848689

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failed to reach statistical significanceno p-value reported

An apparent increase in the OPs amplitude was evident in 6-month old Ins2 Akita mice, but failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.