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Phase III trials of new oral anticoagulants in the acute treatment and secondary prevention of VTE: comparison and critique of study methodology and results.

Adv Ther · 2014 · PMC4033807 · PMID 24821599

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showed a trendno p-value reported
With regard to bleeding rates during acute treatment of patients with VTE, the results varied by the outcome measured, however, both standard measurements, described below, showed a trend to reduction for all four NOACs.

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